Subclinical cardiac dysfunction in children with coeliac disease: Is the gluten free diet effective

dc.contributor.authorŞaylan, Berna
dc.contributor.authorÇevik, Ayhan
dc.contributor.authorTuna Kırsaçlıoğlu, Ceyda
dc.contributor.authorEkici, Filiz
dc.contributor.authorTosun, Özgür
dc.contributor.authorÜstündağ, Gonca
dc.contributor.departmentTıp Fakültesitr_TR
dc.date.accessioned2020-03-20T11:05:23Z
dc.date.available2020-03-20T11:05:23Z
dc.date.issued2012
dc.description.abstractObjectives. The aim of this study is to investigate the effects of coeliac disease on cardiac function in children using conventional transthoracic echocardiography (TTE) and tissue Doppler echocardiography (TDE). Methods. Coeliac disease patients were evaluated in two different groups based on serum endomysial antibody (EmA) titers (EmA (+) and EmA (−)), and the data obtained by conventional and TDE studies were compared between the patient groups and healthy controls. Results. There was no significant difference between EmA (+) and EmA (−) groups in terms of the conventional TTE parameters, including ejection fraction (EF), fractional shortening (FS), and left ventricle end diastolic diameter (LVEDD), that show the left ventricular systolic function (P = 0.727, P = 0.317, P = 0.118). TDE showed a significant difference in left ventricle (LV) isovolumic relaxation time (LV IVRT) and LV myocardial performance index (LV MPI) parameters between EmA (+) and EmA (−) patient groups (P < 0.0001). Conclusion. The measurement of LV MPI and LV IVRT parameters by TDE would be beneficial in early determination of the cardiac involvement and establishing appropriate treatment and followup of patients with coeliac disease as well as in making distinction between EmA (+) and EmA (−) patients.
dc.identifier.urihttps://doi.org/10.5402/2012/706937tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/70744
dc.language.isoentr_TR
dc.relation.isversionof10.5402/2012/706937
dc.relation.journalISRN Gastroenterologytr_TR
dc.relation.publicationcategoryGazete Makalesi - Ulusaltr_TR
dc.subjectCeliac disease, Cardiac dysfunction, Childrentr_TR
dc.titleSubclinical cardiac dysfunction in children with coeliac disease: Is the gluten free diet effectivetr_TR
dc.typeArticletr_TR

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